Download Citation on ResearchGate | Prevención de adherencias peritoneales postoperatorias mediante uso de antagonista de receptores de neurokinina tipo . Las adherencias postoperatorias son actualmente la causa m s frecuente de un padecimiento que todo m dico se enfrenta d a con d a: LA OCLUSI N. Además, Singer y Livesey () indican que un 10% de muertes postoperatorias se debería a la formación de adherencias, valor de mortalidad menor al.

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Arch Med Vet 41, Post-surgical abdominal adhesions in horses: Despite the great number of human and veterinary medicine research, abdominal adhesions are still a big concern and a frequent complication for surgeons. The development of abdominal adhesions is a complex and dynamic process that involves a series of different mechanisms that start with an inflammatory process and tissue damage, followed by a fibrinogenic and fibrinolytic unbalance and ends with a change from fibrin deposit to fibrous tissue.

It is the most frequent cause of recurrent abdominal pain and the second cause for repeat celiotomy. A better understanding of the cellular mechanisms of adhesion formation and reformation should help to develop better prevention methods.

Currently, a variety of prevention measures and treatments, most of them aiming to reduce or avoid adhesions formation, are used in veterinary medicine. The aim of this review is to gather most of the available information and the latest research explaining the pathophysiology, prevention and treatment of abdominal adhesions in horses. En el mismo sentido, Collatos y col reportaron que eventos ocurridos en el sistema vascular no se ven reflejados en la cavidad peritoneal.

Adherencias abdominales postquirúrgicas en equinos: patofisiología, prevención y tratamiento

De manera interesante, cabe mencionar que las adherencias abdominales se conocen por al menos 1. Estas capas proveen un soporte externo a la capa muscular del intestino y mantienen una capa lubricada en la superficie serosa Eggleston y Mueller Por otro lado, PAI-2 ha sido detectado en epidermis, tejido inflamado y placenta, siendo los tipos celulares que expresan PAI-2 queratinocitos, monocitos y trofoblastos respectivamente. El aherencias PA en el peritoneo es t-PA, el cual es inhibido cuando se forma un complejo 1: Hague y col concluyen que el lavado peritoneal reduce la frecuencia de adherencias intraabdominales.


Igualmente, otras combinaciones han sido utilizadas en forma de lavado peritoneal. La carboximetilcelulosa CMC se encuentra actualmente disponible en tres diferentes gamas de pesos moleculares: Los drenajes pueden ser pasivos o activos. Cuando se usan los drenajes pasivos en la cavidad abdominal, se recomienda proteger el extremo del drenaje para prevenir infecciones ascendentes Stone Drains, and external coaptation devices.

An evaluation of low molecular weight heparin postoperztorias hyperbaric oxygen treatment in the prevention of intraabdominal adhesions and wound healing. Am J Surg Enhancement of peritoneal macrophages reduces postoperative peritoneal adhesion formation.

Oostoperatorias Surg Res 58, Preventing intraabdominal adhesions with polylactic acid film: Dis Colon Rectum 48, An experimental study on mice. Dis Colon Rectum 50, Abdominal adhesions after small intestinal surgery in the horse. Vet Surg 18, Intraabdominal adhesions in horses. Compend Contin Educ Pract Vet 13, adherencais Recognizing and managing the postoperative complications of equine abdominal surgery. Vet Med 87, Ann Surg Laparoscopic adhesiolysis in a horse.

Vet Surg 26, Prostaglandins I2 and E2 have a synergistic role in rescuing epithelial barrier function in porcine ileum. J Clin Invest The effect of heparin upon intraabdominal adhesions in rabbits.

Formation and prevention of postoperative abdominal adhesions. J Surg Res Detection of abdominal adhesions in laparoscopic surgery. A controlled study of cases.

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Surg Laparosc Endosc 8, Use of laparoscopic equipment to divide abdominal adhesions in a filly. J Am Vet Med Assoc Evaluation of laparoscopic adhesiolysis for the treatment of postoperahorias induced adhesions in pony foals. Am J Vet Res 63, Peritonitis and peritoneal drainage. Current Practice of Equine Surgery.

postopedatorias Diagnosis and management of peritonitis in horses. In Practice 27, Prevention of tissue injury and postsurgical adhesions by precoating tissues with hyaluronic acid solutions.

J Surg Res 59, Abdominal surgery in foals: Equine Vet J 29, Mast cells facilitate local VEGF release as an early event in the pathogenesis of postoperative peritoneal adhesions. The role of cyclooxygenase inhibitors in the repair of ischaemic-injured jejunal mucosa in the horse. Equine Vet J Suppl 32, Surgical management of periadnexal adhesions.


Int J Fertil 26, Postoperative exposure to glove powders modulates production of peritoneal eicosanoids during peritoneal wound healing. Eur J Surg Hum Reprod Update 7, Vet Clin Equine 15, Regulation of equine fibrinolysis in blood and peritoneal fluid based on a study of colic cases and induced endotoxaemia.

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Equine Adherencizs J adhrrencias, Prevention of postsurgical adhesions with N,O-carboxymethyl chitosan: Reduction of postoperative adhesions by N,O-carboxymethylchitosan: Fertil Steril 80, Sisson S, Grossman JD eds. Plasma levels of t-PA and PAI-1 correlate with the formation of experimental post-surgical peritoneal adhesions. Mediators Inflamm The peritoneum and its response to surgical injury.

Prog Clin Biol Res Peritoneal repair and post-surgical adhesion formation. Manual of Equine Gastroenterology. Postoperative intraperitoneal adhesion pathophysiology. Colorectal Disease 9, In vivo evaluation of a collagenous membrane as an absorbable adhesion barrier.

J Biome Mater Res 34, Prevention and treatment of gastrointestinal adhesions. The aetiology of postoperative abdominal adhesions. Br J Surg 50, Evidence for incorporation of free-floating mesothelial cells as a mechanism of serosal healing. J Cell Sci Postoperative adhesive peritoneal disease. Surg Endosc 8, adheencias Short-and long-term survival postopeeratorias prevalence of post operative ileus after small intestinal surgery in the horse.

Current Practice of equine Surgery. Intraabdominal adhesions in horses: Vet J Low-dose heparin in experimental peritonitis. Eur Sur Res 17, Evaluation of postoperative peritoneal lavage in standing horses for prevention of experimentally induced abdominal adhesions.

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Vet Surg 27, Anaesthesia of the horse. Evaluation of peritoneal fluid following intestinal resection and anastomosis in horses. Am J Vet Res 53,